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0 0.5 1 1.5 2+ Mortality 24% Improvement Relative Risk Progression -7% Case -11% c19aspirin.com Son et al. Aspirin for COVID-19 Prophylaxis Favors aspirin Favors control
Son, 11,475 patient aspirin prophylaxis PSM study: 24% lower mortality [p=0.52], 7% higher progression [p=0.8], and 11% more cases [p=0.21] https://c19p.org/son
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Effect of aspirin on coronavirus disease 2019
Son et al., Medicine, doi:10.1097/MD.0000000000026670
30 Jul 2021    Source   PDF   Share   Tweet
PSM retrospective case control study in South Korea, showing a trend towards lower mortality, but no significant differences with aspirin use.
risk of death, 24.0% lower, OR 0.76, p = 0.52, treatment 37 of 128 (28.9%) cases, 31 of 128 (24.2%) controls, case control OR, group 1, model 2 (most data in group and adjustments).
risk of progression, 7.0% higher, OR 1.07, p = 0.80, treatment 77 of 339 (22.7%) cases, 58 of 339 (17.1%) controls, case control OR, complications, group 1, model 2 (most data in group and adjustments).
risk of case, 11.0% higher, OR 1.11, p = 0.21, treatment 313 of 3,825 (8.2%) cases, 617 of 7,650 (8.1%) controls, case control OR, group 1, PSM 1, model 2 (most data in group and adjustments).
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Son et al., 30 Jul 2021, retrospective, propensity score matching, South Korea, peer-reviewed, 6 authors.
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