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Aspirin study #1   All Outcomes
0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Case 71% Imp. Relative Risk, 95% CI Huh: Association of previous medications with the risk of COV.. c19aspirin.com/huh3.html Favors aspirin Favors control
5/18 Prophylaxis study
Huh et al., medRxiv, doi:10.1101/2020.05.04.20089904 (Preprint)
Association of previous medications with the risk of COVID-19: a nationwide claims-based study from South Korea
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Retrospective database analysis of 65,149 in South Korea, showing significantly lower cases with existing aspirin treatment. The journal version of this paper does not present the aspirin results (only combined results for NSAIDs).
risk of case, 71.0% lower, RR 0.29, p = 0.001, treatment 8 of 543 (1.5%), control 5,164 of 64,606 (8.0%), adjusted per study.
Huh et al., 5/18/2020, retrospective, database analysis, South Korea, Asia, preprint, 10 authors.
Contact: eastside1st@gmail.com.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
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