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Home   COVID-19 treatment studies for Aspirin  COVID-19 treatment studies for Aspirin  C19 studies: Aspirin  Aspirin   Select treatmentSelect treatmentTreatmentsTreatments
Antiandrogens (meta) Metformin (meta)
Aspirin (meta) Molnupiravir (meta)
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Aspirin study #8   All Outcomes
0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Case 28% Imp. Relative Risk, 95% CI Mortality 62% Time to viral- 10% Time to viral- (b) 15% Merzon: The use of aspirin for primary prevention of cardiovascu.. c19aspirin.com/merzon2.html Favors aspirin Favors control
2/23 Prophylaxis study
Merzon et al., The FEBS Journal, doi:10.1111/febs.15784 (Peer Reviewed)
The use of aspirin for primary prevention of cardiovascular disease is associated with a lower likelihood of COVID-19 infection
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Retrospective 10,477 patients in Israel, showing lower risk of COVID-19 cases with existing aspiring use.
risk of case, 27.6% lower, RR 0.72, p = 0.04, treatment 73 of 1,621 (4.5%), control 589 of 8,856 (6.7%), adjusted per study, odds ratio converted to relative risk.
risk of death, 62.4% lower, RR 0.38, p = 0.51, treatment 1 of 21 (4.8%), control 6 of 91 (6.6%), adjusted per study, odds ratio converted to relative risk.
time to viral-, 9.6% lower, relative time 0.90, p = 0.04, treatment 73, control 589, time to 2nd negative test.
time to viral-, 14.8% lower, relative time 0.85, p = 0.005, treatment 73, control 589, time to 1st negative test.
Merzon et al., 2/23/2021, retrospective, Israel, Middle East, peer-reviewed, 8 authors.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
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