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Home   COVID-19 treatment studies for Aspirin  COVID-19 treatment studies for Aspirin  C19 studies: Aspirin  Aspirin   Select treatmentSelect treatmentTreatmentsTreatments
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0 0.5 1 1.5 2+ Case 28% Improvement Relative Risk Mortality 62% Time to viral- 10% Time to viral- (b) 15% c19aspirin.com Merzon et al. Aspirin for COVID-19 Prophylaxis Favors aspirin Favors control
Merzon, 10,477 patient aspirin prophylaxis study: 28% fewer cases [p=0.04] and 10% faster viral clearance [p=0.05] https://c19p.org/merzon2
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The use of aspirin for primary prevention of cardiovascular disease is associated with a lower likelihood of COVID-19 infection
Merzon et al., The FEBS Journal, doi:10.1111/febs.15784
23 Feb 2021    Source   PDF   Share   Tweet
Retrospective 10,477 patients in Israel, showing lower risk of COVID-19 cases with existing aspiring use.
risk of case, 27.6% lower, RR 0.72, p = 0.04, treatment 73 of 1,621 (4.5%), control 589 of 8,856 (6.7%), NNT 47, adjusted per study, odds ratio converted to relative risk.
risk of death, 62.4% lower, RR 0.38, p = 0.51, treatment 1 of 21 (4.8%), control 6 of 91 (6.6%), adjusted per study, odds ratio converted to relative risk.
time to viral-, 9.6% lower, relative time 0.90, p = 0.045, treatment 73, control 589, time to 2nd negative test.
time to viral-, 14.8% lower, relative time 0.85, p = 0.005, treatment 73, control 589, time to 1st negative test.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Merzon et al., 23 Feb 2021, retrospective, Israel, peer-reviewed, 8 authors.
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