Malik, 310 patient aspirin prophylaxis study: 14% lower mortality [p=0.72], 28% lower ICU admission [p=0.17], 25% lower ARDS [p=0.39], and 2% lower hospitalization [p=0.94] https://c19p.org/malik
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Effect of low dose acetylsalicylic acid and anticoagulant on clinical outcomes in COVID‐19, analytical cross‐sectional study
et al., Health Science Reports, doi:10.1002/hsr2.699
Retrospective 539 patients in the USA, showing lower mortality, ICU admission, and ARDS with aspirin treatment, without statistical significance.
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risk of death, 13.6% lower, RR 0.86, p = 0.72, treatment 15 of 87 (17.2%), control 24 of 223 (10.8%), adjusted per study, odds ratio converted to relative risk, multivariable.
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risk of ICU admission, 27.8% lower, RR 0.72, p = 0.17, treatment 28 of 87 (32.2%), control 77 of 223 (34.5%), adjusted per study, odds ratio converted to relative risk, multivariable.
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risk of ARDS, 25.1% lower, RR 0.75, p = 0.39, treatment 13 of 87 (14.9%), control 40 of 223 (17.9%), NNT 33, adjusted per study, odds ratio converted to relative risk, multivariable.
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risk of hospitalization, 2.4% lower, OR 0.98, p = 0.94, treatment 25, control 176, adjusted per study, multivariable, RR approximated with OR.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Malik et al., 7/11/2022, retrospective, USA, peer-reviewed, 16 authors, study period 1 March, 2020 - 1 December, 2020.
Contact:
muhammadbmalik@gmail.com, dr_samar11@yahoo.com.
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